THE THEORY OF ALLERGIC ULCER DISEASE | BIONATURE

Peptic ulcers affect roughly 10% of the population in most nations. The incidence of sensensitivity to ten common allergens was compared in a sample of 1000 nonselected patients with recurrent peptic ulcers and 100 healthy control persons. Skin reactions to three or more allergens were found to be strongly positive in 46.7 percent of ulcer patients and 10% of control subjects, respectively. House dust, grass, trees, and weedspollen moulds, cockroaches, and various food allergens, including milk, fruits, and vegetables, were the most commonly sensitised allergens in patients. Several patients had a very close association between their sensitivity to plant allergens and the return of ulcers during the spring and summer months.

These findings tend to indicate that in predisposed people with genetic or acquired types of atopic diathesis, upper gastrointestinal tract tissue, particularly gastic and/or duodenal mucosa, becomes sensitive to a variety of dietary and inhalation allergens. The entire IgE-producing cell may be identified in the mucosa of the stomach and/or dudenum in the cases mentioned above.

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